When submitting a course run for review, if there is an issue with the course, but not with the course run, it will show up with an error message from the course, but still have been put into review by the course run since they are separate requests.
Steps to reproduce:
The way I did it is to take a Verified or Professional entitlement course that has already been scheduled (so official version exists) and then change the mode of the entitlement. This will cause an error for the course about switching modes, but the course run will still go into review. A subsequent refresh will show the course and course run in review or if you try and save or submit again, you will receive an error about not being able to edit because the run is in review.
If the course has an error when being submitted for review, the course run should not go into review.